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Prior to his position as Executive Director of Mental and Physical Health, Klepp served as the Director General for Public Health at the Norwegian Directorate of Health (2006-2015). He is an adjunct professor at the University of Oslo where he served as a full professor in public health nutrition from 1996-2006. Prior to this he was a professor in international health promotion at the University of Bergen, Norway.
Klepp has published more than 250 papers in peer reviewed journals, primarily in the fields of adolescent health promotion, nutrition and hiv/aids prevention. He has coordinated and served as investigator on a large number of European Union research project, and he has extensive research experience from Eastern and Southern Africa. Klepp has been involved in the WHO recent efforts to reduce non-communicable diseases, and he has chaired the WHO Euro member state network on reducing marketing pressure on children since 2008.
Klepp has served as chair of the Norwegian National Council on Nutrition and Physical Activity, and he has chaired research programmes on public health within the Norwegian Research Council. He was President of the International Society of Behavioural Nutrition and Physical Activity from 2010 to 2011.